Laboratory technician in protective gear examining vials in a pharmaceutical manufacturing facility.

Opcenter Execution Pharma

The platform to win the race against time provides electronic batch records (eBR) for the pharmaceutical industry.

Successfully fast-track lab and production

Opcenter Execution Pharma enables more than paperless production: It’s the constantly evolving digital platform that helps pharmaceutical companies to develop and produce new drugs and vaccines faster than ever.

Time is precious and quality is essential

The orchestration of development and production in the pharmaceutical industry requires a powerful manufacturing execution system (MES). Opcenter Execution Pharma seamlessly integrates MES functionality, automation, and enterprise resource planning (ERP) systems. It enables you to streamline processes and operations in full compliance with regulations thanks to complete paperless manufacturing and full electronic batch recording. In short: It’s the decisive tool for greater competitiveness.

Design, execute, and review along the entire lifecycle

Design, guide, control and review the product and production lifecycles by providing an electronic batch record that precisely details how a drug has been produced as required by FDA, CFDA and European regulatory bodies.

Design

Develop, use, and reuse standard processes and sub-processes through an intuitive tool. There are no IT skills required.

Execute

Benefit from faster and safer data acquisition thanks to a guided and controlled paperless process.

Review

There’s a single point of review of all batch relevant information, which ultimately enables review by exception.

Every functionality you need at your fingertips

Master batch records (MBR)

Graphical workflows, text editor design, pre-built work elements, and parameter management

Material management

Inbound process (goods receipt, sampling, QC), picking and requisitioning, tracking and tracing, and outbound process (goods issue, shipping)

Weighing and dispense

Scale management and calibration check, 16 predefined weighing methods, tolerance, potency and density calculations, check in/out of prepared materials

Enterprise integration

Interface to other business and manufacturing systems, standard connectors, integration with Opcenter APS and Opcenter Laboratory

Electronic batch record

Guidance and electronic instructions, compatible with tactile environment, real-time control, deviation management and release by exception

Equipment management

Classes and properties, fixed, mobile, single use or reusable, advanced life cycle configuration, equipment logbook

Packaging

Line management instructions, in process quality control, material replenishment, concordance calculation and reconciliation

Automation integration

OPC and OPC UA client, integration of MES task list in HMI, native integration with SIMATIC PCS7 and SIMATIC Batch

eBR in the cloud

Providing eBR as a managed service

The goal for future releases of our eBR Apps Suite is to provide eBR services and apps. We want to make the deployment of a paperless batch record system more affordable through cloud-based infrastructure. Moreover, we’re going to enable you to build new apps with a low-code application development platform.

Person in lab coat examining test tubes in a laboratory setting

Discover, what’s new in Opcenter Execution Pharma

Opcenter Execution Pharma (EX PH) software supports rapid change, lean paperless manufacturing, and consistent quality output. It integrates the manufacturing execution system (MES) with the distributed control system (DCS), expediting design, execution, and review of manufacturing steps. Opcenter EX PH 2025, part of Siemens Xcelerator, enables users to regulate and manage processes without paper-based procedures or documents. With Opcenter EX PH, you can easily configure and leverage out-of-the-box (OOTB) functionality to facilitate design processes even without specific IT skills.

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