MADE is a Competence Center for Industry 4.0 that simulates a digital factory, created to carry out orientation, training, and finalization of technology transfer projects with Italian companies, particularly SMEs, on Industry 4.0 issues. A technical interlocutor that companies can contact to be supported during the digital transition towards a smart factory, with the aim of keeping their profile high, competitive, and sustainable. MADE4.0 is a reality created by MISE (Italian Ministry of Economic Development) and is coordinating 25 European Digital Innovation Hub of the most competitive European Regions representing more than 30% of manufacturing EU added value.