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Why Simcenter M-Star?

Simcenter M-Star is purpose-built for mixing and bioprocess applications. It enables engineers and scientists to simulate transient mixing and process flows involving liquids, gases, particles, heat transfer and multiphase phenomena using a GPU-native lattice Boltzmann solver. Its GPU-native architecture accelerates simulation speed while enabling high-fidelity physics at scale. With an intuitive workflow and integrated analysis tools, Simcenter M-Star helps organizations reduce development time, improve process parameters and accuracy and bring innovative products to market faster.

Bioreactor mixing process with submerged agitator blades creating turbulent flow and bubbles in liquid medium.

Accelerate simulations with GPU power

Run complex transient CFD and multiphysics simulations significantly faster using a GPU-native solver designed to efficiently handle large-scale models without compromising accuracy.

Capture real-world physics

Capture transient mixing, particle suspension, aeration, heat transfer and multiphase interactions with high-fidelity lattice Boltzmann technology for more reliable engineering insights.

Streamline engineering workflows

Move from geometry to results in a unified environment with integrated preprocessing, postprocessing and visualization capabilities.

Featured capabilities

Intuitive workflow

Simcenter M-Star delivers a "Day 1" production workflow through an intuitive interface that eliminates the need for complex CAD cleanup and traditional volume meshing. This allows users to move from raw geometry to high-fidelity simulation results in just hours rather than days.

Accelerated simulation

Simcenter M-Star’s performance is driven by the lattice Boltzmann method (LBM) mapped onto graphics processing unit (GPU) architectures. This powerful combination delivers unprecedented speedups, transforming weeks of complex computation into actionable overnight answers. By leveraging this GPU-native LBM solver, engineers can fundamentally accelerate their workflow while achieving higher fidelity.

Illustration showing Lattice Boltzmann Method (LBM) accelerated by GPU processing for faster simulations.

Transient physics

Simcenter M-Star enables the real-time prediction of transient 3D physics, empowering engineers to accurately capture the true, time-evolving nature of complex fluid processes. By specifying custom fluid properties and precise operating conditions, teams can gain deeper insights into chaotic mixing dynamics.

Validated predictions

Simcenter M-Star provides a validated Digital Twin for scale-up and design decisions, delivering high-fidelity predictions that are backed by extensive peer-reviewed literature and a broad validation against experimental measurements and benchmark studies.

See technical papers

Technical papers and validation reports demonstrating verified simulation accuracy and predictive reliability.

Getting started with Simcenter M-Star

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Bioreactors

Most biologic processes are developed in lab-scale tabletop bioreactors with small operating volumes. Simcenter M-Star CFD helps you scale up processes from lab-scale to production-scale build with greater speed and fidelity than ever before.

Bioreactor simulation showing fluid mixing, gas dispersion, dissolved oxygen levels, and velocity distribution.

View additional resources

Watch

Webinar | Real-time CFD-bioreactor models with integrated process control
Webinar | Best practices for bioreactor CFD
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Read

Technical paper | High-fidelity CFD up to 200× faster than finite-volume CFD
Technical paper | Validating lattice boltzmann LES for biopharma equipment
View all technical papers

Frequently asked questions